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Journal of Molecular Biology
Published by Elsevier.
ISSN 0022-2836 / 1089-8638
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Aims & scope
Journal of Molecular Biology publishes peer-reviewed research. Manuscripts pass a technical check and a scope check by the handling editor before going to independent reviewers.
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Recently published
Recurrent Catalytic-site Change and Electrostatic Remodeling Across the HEPN Ribonuclease Fold
DOI 10.1016/j.jmb.2026.170055 Marc Zimmer · 2027
Ribosomal Protein eL22 Contributes to the Assembly of 60S Ribosomal Subunits in Saccharomyces cerevisiae
DOI 10.1016/j.jmb.2026.170065 José Fernández-Fernández, Sara Martín-Villanueva, Taylor N. Ayers, Carla V. Galmozzi, John L. Woolford, Jesús de la Cruz · 2027
Differential Recognition of β-catenin and TRIP6 by MAGI1 PDZ6 and Allosteric Modulation by DLL1
DOI 10.1016/j.jmb.2026.170057 Valeria Pennacchietti, Cosmin Marian Obreja, Rodolfo Ippoliti, Stefano Gianni, Francesca Malagrinò · 2027
Lactate-associated H3K18 Lactylation and SYT8 in the Temozolomide Response of Glioblastoma Cells
DOI 10.1016/j.jmb.2026.170064 Sansong Chen, Yiming Deng, Limin Cheng · 2027
Suramin and Its Analogues Are Multi-functional Inhibitors of cGAS
DOI 10.1016/j.jmb.2026.170044 Xiaoman An, Jingwen Wang, Benzhen Duan, Yang Xiao, Yunxiao Huang, Hongyu Zhao, Meng Zhang, Kunsheng Tao, Qian Wang, Fenglei Du, Lili Zhu, Baoyu Zhao · 2026
Structural Basis of Substrate Accommodation and Thiourea-mediated Inhibition of the Mycobacterium tuberculosis Dehydratase HadAB
DOI 10.1016/j.jmb.2026.170053 Soumya Sarathi Ganguly, Rituparna Saha, Bina Kumari Singh, Soumya De, Amit Kumar Das · 2026
Tandem-Affinity Crosslinking Mass Spectrometry Supports a Model of a DNA-PKcs–PP6 Regulatory Complex
DOI 10.1016/j.jmb.2026.170051 Danny Laurent, Morgan F. Khan, Morgan Hepburn, Miaw-Sheue Tsai, Justin La, Binhang Zhu, Mariia Mikhova, Jens Schmidt, Susan P. Lees-Miller, David C. Schriemer · 2026
TAD Boundary Disruption in Xq27–q28 Deletions Rewires 3D Chromatin Architecture and May Predispose to Primary Skewed X Chromosome Inactivation
DOI 10.1016/j.jmb.2026.170040 Kimiko Katoh, Hiroyo Nishide, Yu Hamaguchi, Minami Soga, Kaori Aiba, Kagayaki Kato, Motosuke Tsutsumi, Joe Sakamoto, Elena Solovieva, Tomomi Nemoto, Takumi Era, Michiaki Hamada, Ikuo Uchiyama, Nobuaki Wakamatsu, Masato Asai · 2026
TISON: A Web Server for Omics-driven Integrative Cancer Modeling & Simulations Towards Personalized Medicine
DOI 10.1016/j.jmb.2026.170025 Zainab Nasir, Muhammad Umer Sultan, Mahnoor Naseer Gondal, Zain Bin Tanveer, Ammar Arif, Rida Nasir Butt, Abdul Rehman, Hira Anees Awan, Muhammad Faizyab Ali Chaudhary, Zainab Arshad, Waleed Ahmed, Ghulam Mustafa, Salaar Khan, Talha Ahmad Khan, Bibi Amina, Muhammad Farhan Khalid, Risham Hussain, Huma Khawar, Adan Tanveer, Sakina Ali Asghar, Shaoor Ahmad Khan, Sadia Mahmood, Rahma Ijaz, Osama Shiraz Shah, Hadia Hameed, Ammar Khan, Rida Akbar, Mahum Azhar, Susana Alam, Anmol Karim, Sameera Arzoo, Muhammad Farooq Ahmad Butt, Murtaza Taj, Sameer Ahmed, Syed Waqar Nabi, Wim Vanderbauwhede, Emad Ud Din, Fayyaz Ahmed, Aejaz Nasir, Amir Faisal, Usman Majeed, Safee Ullah Chaudhary · 2026
DC+: A Web Server for the Analysis of Residual Dipolar Couplings
DOI 10.1016/j.jmb.2026.170054 Yang Shen, Frank Delaglio, Ad Bax · 2026
Opposing Effects of Periplasmic Chaperones on Protein Folding
DOI 10.1016/j.jmb.2026.169966 Deep Chaudhuri, Madhu Bhatt, Shubhasis Haldar · 2026
Expanding the Landscape of Disordered Flexible Linkers: A Structural and Computational Framework for DLD Dataset Assembly
DOI 10.1016/j.jmb.2026.169994 Di Meng, Juliana Glavina, Heli M. Garcia Alvarez, Cesar Osvaldo Leonetti, Gianluca Pollastri, Lucía B. Chemes · 2026
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