Crossref indexed

Regulatory Toxicology and Pharmacology

Published by Elsevier.

ISSN 0273-2300 / 1096-0295

Aims & scope

Regulatory Toxicology and Pharmacology publishes peer-reviewed research. Manuscripts pass a technical check and a scope check by the handling editor before going to independent reviewers.

Recently published

Next-generation risk assessment of resveratrol: An external exposure approach based on comprehensive read-across with independent internal exposure verification

Tomoka Hisaki, Takumi Nukaga, Tomomi Atobe, Munetaka Kawamoto, Shuichi Sekine, Akiko Tamura, Morihiko Hirota · 2027

DOI 10.1016/j.yrtph.2026.106264

Beyond kratom: Concentrated 7-hydroxymitragynine and mitragynine pseudoindoxyl products, an MME potency assessment

Jonathan Heywood, Helen Farnham, Elizabeth Jackson, Katie Steimel, Sarah Brown, Alexander Riordan · 2027

DOI 10.1016/j.yrtph.2026.106272

Biomonitoring to assess the pesticides exposure of rural workers: An elucidative and critical review

Luiz Filipe Costa, Raquel Jorgeta de Lima, Alysson Januario Inacio da Freiria, Otávio Bertolino de Lima, Wesley Rodrigues Barcelos Fernandes, Leonardo Hideki Watanabe, João Pedro Santiago Vigato, Rafael Araújo Silva, Isarita Martins · 2027

DOI 10.1016/j.yrtph.2026.106270

Trichloroethylene-associated hypersensitivity: Clinical patterns supporting an idiosyncratic solvent-induced liver injury framework

Young Joong Kang, Woncheol Lee, Seongmin Jo, Jung-Min Sung, Jae-Hyug Woo · 2027

DOI 10.1016/j.yrtph.2026.106266

New approach methodologies in pharmaceutical development: Survey insights on adoption, infrastructure, and the path to broader implementation

Jessica C. Graham, Brandy Morenko, Damodaran Annamalai, Fatima Arjmand, Monika Burns, Danielle Elbirt, Brianna N. Gaskill, Moran Grossman, Dawn S.Y. Lin, Kathy Orsted, Rosemary Santos, Alanna Sedgwick, Margit Spatzenegger · 2027

DOI 10.1016/j.yrtph.2026.106267

Williams et al. (2000) retraction not supported by the facts and should be reinstated in the literature

Donna Farmer, David Saltmiras · 2027

DOI 10.1016/j.yrtph.2026.106248

Hazard characterization and dietary risk assessment of pentachlorothiophenol in food using health-based guidance values based on a read-across approach

Adebayo J. Akinboye, Jiyeon Yang, Junhyeong Park, Jeongho Oh, Taeyoung Yu, Joon-Goo Lee · 2027

DOI 10.1016/j.yrtph.2026.106273

Applicability of the ICH M7 guidelines for assessing less-than-lifetime exposure to nitrosamine impurities in drug products

Susan P. Felter, Joel P. Bercu, Robert A. Jolly, Timothy J. McGovern, Yi Yang, Alejandra Trejo-Martin, Roland Froetschl, Bodo Haas, Kelly Brant, Alisa Vespa, David J. Ponting, Anthony Lynch, Ashley M. Mudd, Angela White, Andreas Zeller, Raechel Puglisi · 2027

DOI 10.1016/j.yrtph.2026.106245

Safety evaluation of sub-chronic oral exposure to ochratoxin A and citrinin in Wistar rats

Pankaj Ramji Jagdale, Sourin Adhikary, Indra Dev, Anjaneya Ayanur, Mahadeo Kumar, Dhirendra Singh, Md Arshad, Kausar Mahmood Ansari · 2027

DOI 10.1016/j.yrtph.2026.106271

Mutagenicity studies on migrants from food-contact silicone products based on Ames test and chemical analysis

Peixue Guo, Zhaoxi Liu, Jin Rong, Xueting Feng, Xiaojie Fan, Di Feng · 2027

DOI 10.1016/j.yrtph.2026.106274

Acute and sub-acute toxicity evaluation of rhamnolipid derived from Stutzerimonas stutzeri PS1 in Wistar rats

Suvarna R. Umape, Nisha A. Nerlekar, Arati S. Kulkarni, Dhiraj Y. Shivsharan, Padma B. Dandge · 2027

DOI 10.1016/j.yrtph.2026.106280

Response to the letter to the editor “Confidence in New Approach Methods (NAMs): Ensuring reproducibility, operationalising context-of-use and alignment with decision-making needs”

G. Ouedraogo, N. Alépée, B. Tan, C.S. Roper · 2027